violetFluor™ 450 Anti-Human CD20 (2H7)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 75-0209-T025 | 25 tests | $109.00 | ||
| 75-0209-T100 | 100 tests | $230.00 | ||
| 75-0209-T500 | 500 tests | $1,035.00 |
Technical Data Sheet
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The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.
The 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.
The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.
The 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.
Product Details
| Name | violetFluor™ 450 Anti-Human CD20 (2H7) |
|---|---|
| Cat. No. | 75-0209 |
| Alternative Names | B1, Leu-16, Bp35 |
| Gene ID | 931 |
| Clone | 2H7 |
| Isotype | Mouse IgG2b, kappa |
| Reactivity | Human |
| Cross Reactivity | Baboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, Squirrel Monkey |
| Format | violetFluor™ 450 |
| Application | Flow Cytometry |
| Citations* |
Liu AY, Robinson RR, Murray Jr ED, Ledbetter JA, Hellstrom I and Hellstrom KE. 1987. J Immunol. 139(10): 3521-3526. Schlossman S, Bloumsell L, et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. Deans JP, Kalt E, Ledbetter JA, Schieven GL, Bolen JB and Johnson P. 1995. J Biol Chem. 270: 22632-22638. (Flow cytometry) Polyak MJ and Deans JP. 2002. Blood. 99(9): 3256-3262. (Flow cytometry, Immunoprecipitation) Brown KN, Trichel A and Barratt-Boyes SM. 2007. J Immunol. 178(11): 6958-6967. (Flow cytometry - Rhesus) |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.