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Recombinant Mouse Persephin (Carrier-free)
  • Recombinant Mouse Persephin (Carrier-free)

Recombinant Mouse Persephin (Carrier-free)

Cat No. Size Price Quantity
21-7081-U005 5 µg $76.00
21-7081-U020 20 µg $175.00
21-7081-U100 100 µg $585.00
21-7081-U500 500 µg $1,795.00

Description

Persephin (PSP) is a secreted protein that belongs to the family of neurotrophic factors that includes GDNF, neurturin (NTN) and artemin, all distantly related to the TGF-beta superfamily. Neurotrophic factors play in a role in development and maintenance of the nervous system. Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development, but does not support the peripheral nervous system. Persephin does not seem to signal through the same receptor complexes as other family members GDNF and NTN, but uses GFR alpha-4.
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Persephin (PSP) is a secreted protein that belongs to the family of neurotrophic factors that includes GDNF, neurturin (NTN) and artemin, all distantly related to the TGF-beta superfamily. Neurotrophic factors play in a role in development and maintenance of the nervous system. Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development, but does not support the peripheral nervous system. Persephin does not seem to signal through the same receptor complexes as other family members GDNF and NTN, but uses GFR alpha-4.
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Product Details

Name Recombinant Mouse Persephin (Carrier-free)
Cat. No. 21-7081
Alternative Names PSP, PSPN
Amino Acid Sequence ALAGSCRLWS LTLPVAELGL GYASEEKVIF RYCAGSCPQE ARTQHSLVLA RLRGRGRAHG RPCCQPTSYA DVTFLDDQHH WQQLPQLSAA ACGCGG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined by its ability to stimulate proliferation of human thyroid carcinoma cells (TT cells) is < 0.1 ng/ml, corresponding to a specific activity of ≥≥>1 x 107 un
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse Persephin is a disulfide-linked homodimer, composed of two 10.3 kDa polypeptide chains (96 total amino acid residues). Each chain contains seven conserved cysteine residues, one of which (Cys 63) is used for inter-chain disulfide bridgi
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Neurobiology; TGF-beta Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.