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Recombinant Mouse Midkine (Carrier-free)
  • Recombinant Mouse Midkine (Carrier-free)

Recombinant Mouse Midkine (Carrier-free)

Cat No. Size Price Quantity
21-7113-U005 5 µg $76.00
21-7113-U020 20 µg $175.00
21-7113-U100 100 µg $585.00
21-7113-U500 500 µg $1,795.00

Description

Midkine, also known as neurite growth-promoting factor 2, is a heparin-binding nonglycosylated low molecular weight protein. It is expressed in a variety of cell types during embryogenesis, and has functions related to cell growth, migration and angiogenesis. Midkine signals through the anaplastic lymphoma kinase (ALK) receptor which stimulates phosphorylation and kinase activation events and results in cell proliferation.
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Midkine, also known as neurite growth-promoting factor 2, is a heparin-binding nonglycosylated low molecular weight protein. It is expressed in a variety of cell types during embryogenesis, and has functions related to cell growth, migration and angiogenesis. Midkine signals through the anaplastic lymphoma kinase (ALK) receptor which stimulates phosphorylation and kinase activation events and results in cell proliferation.
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Product Details

Name Recombinant Mouse Midkine (Carrier-free)
Cat. No. 21-7113
Alternative Names MK, NEGF-2, neurite growth-promoting factor 2, ARAP, amphiregulin-associated protein, MDK, MEK, MK1, midgestation and kidney protein, MKARAP
Amino Acid Sequence VAKKKEKVKK GSECSEWTWG PCTPSSKDCG MGFREGTCGA QTQRVHCKVP CNWKKEFGAD CKYKFESWGA CDGSTGTKAR QGTLKKARYN AQCQETIRVT KPCTSKTKSK TKAKKGKGKD
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Within a concentration range of 10-100 ng/ml, the ability to chemoattract human neutrophils is measured.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse Midkine consists of 120 amino acid residues including five intra-molecular disulfide bonds, and has a molecular weight of 13.3 kDa.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Angiogenesis & Cardiovascular, Neurobiology
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.