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Recombinant Mouse IL-9 (Carrier-free)
  • Recombinant Mouse IL-9 (Carrier-free)

Recombinant Mouse IL-9 (Carrier-free)

Cat No. Size Price Quantity
21-8952-U002 2 µg $69.00
21-8952-U010 10 µg $179.00
21-8952-U100 100 µg $1,025.00
21-8952-U500 500 µg $3,100.00

Description

IL-9 is an immunoregulatory cytokein that is expressed by activated Th9, Th17, Treg and Th2 cells. It signals through the IL-9 receptor, where the IL-9R alpha chain and the common gamma chain (CD132) interact to form the active receptor complex. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Although mouse IL-9 is active on human cells, human IL-9 is inactive on mouse cells.
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IL-9 is an immunoregulatory cytokein that is expressed by activated Th9, Th17, Treg and Th2 cells. It signals through the IL-9 receptor, where the IL-9R alpha chain and the common gamma chain (CD132) interact to form the active receptor complex. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Although mouse IL-9 is active on human cells, human IL-9 is inactive on mouse cells.
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Product Details

Name Recombinant Mouse IL-9 (Carrier-free)
Cat. No. 21-8952
Alternative Names p40 cytokine, T cell growth factor p40
Amino Acid Sequence MQRCSTTWGI RDTNYLIENL KDDPPSKCSC SGNVTSCLCL SVPTDDCTTP CYREGLLQLT NATQKSRLLP VFHRVKRIVE VLKNITCPSF SCEKPCNQTM AGNTMSFLKS LLGTFQKTEM QRQKSRP
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 as determined by the dose-dependent proliferation of human MO7e cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between ≥ ≥ ≥ the human and mouse proteins.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Cancer; Proliferation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.