Recombinant Mouse IL-6 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8061-U002 | 2 µg | $48.00 | ||
| 21-8061-U010 | 10 µg | $125.00 | ||
| 21-8061-U100 | 100 µg | $525.00 | ||
| 21-8061-U500 | 500 µg | $1,596.00 |
Technical Data Sheet
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IL-6 is a pleiotropic cytokine produced by a variety of cell types including T cells, monocytes, fibroblasts, endothelial cells and keratinocytes. IL-6 has diverse functions including important roles in the acute phase reaction, inflammation, hematopoiesis, and bone metabolism.
IL-6 is a pleiotropic cytokine produced by a variety of cell types including T cells, monocytes, fibroblasts, endothelial cells and keratinocytes. IL-6 has diverse functions including important roles in the acute phase reaction, inflammation, hematopoiesis, and bone metabolism.
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Product Details
| Name | Recombinant Mouse IL-6 (Carrier-free) |
|---|---|
| Cat. No. | 21-8061 |
| Alternative Names | 26 kDa protein, IFN-g2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 |
| Amino Acid Sequence | MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥≥ ? 5 x 107 units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Mouse IL-6 is a 21.7 kDa protein composed of 187 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Mouse |
| Research Areas | Angiogenesis/Cardiovascular; Cancer; Cell Culture; Diabetes / Weight Regulation; Immune System; Inflammation; Neurobiology; Stem Cells & Differentiation; Wound Healing; Allergy; Transplantation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.