Recombinant Mouse IL-5 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8051-U005 | 5 µg | $63.00 | ||
| 21-8051-U025 | 25 µg | $191.00 | ||
| 21-8051-U100 | 100 µg | $549.00 | ||
| 21-8051-U500 | 500 µg | $1,696.00 |
Technical Data Sheet
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IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced mainly by Th2 cells, IL-5 can also be produced by mast cells and activated eosinophils. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Mouse IL-5 is cross-reactive with the human IL-5 receptor.
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced mainly by Th2 cells, IL-5 can also be produced by mast cells and activated eosinophils. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Mouse IL-5 is cross-reactive with the human IL-5 receptor.
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Product Details
| Name | Recombinant Mouse IL-5 (Carrier-free) |
|---|---|
| Cat. No. | 21-8051 |
| Alternative Names | EDF, BCDFII, TRF |
| Amino Acid Sequence | MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | ED50 < 2.0 ng/ml, calculated as specific activity activity of ≥≥>5 x 105 units/mg determined by dose-dependent proliferation of human TF-1 cells. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Mouse IL-5 is a 26.2 kDa homodimeric protein containing two 113 amino acid chains. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Mouse |
| Research Areas | Immune System; Inflammation; Proliferation; Wound Healing; Allergy |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.