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Recombinant Mouse IL-5 (Carrier-free)
  • Recombinant Mouse IL-5 (Carrier-free)

Recombinant Mouse IL-5 (Carrier-free)

Cat No. Size Price Quantity
21-8051-U005 5 µg $63.00
21-8051-U025 25 µg $191.00
21-8051-U100 100 µg $549.00
21-8051-U500 500 µg $1,696.00

Description

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced mainly by Th2 cells, IL-5 can also be produced by mast cells and activated eosinophils. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Mouse IL-5 is cross-reactive with the human IL-5 receptor.
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IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced mainly by Th2 cells, IL-5 can also be produced by mast cells and activated eosinophils. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Mouse IL-5 is cross-reactive with the human IL-5 receptor.
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Product Details

Name Recombinant Mouse IL-5 (Carrier-free)
Cat. No. 21-8051
Alternative Names EDF, BCDFII, TRF
Amino Acid Sequence MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity ED50 < 2.0 ng/ml, calculated as specific activity activity of ≥≥>5 x 105 units/mg determined by dose-dependent proliferation of human TF-1 cells.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse IL-5 is a 26.2 kDa homodimeric protein containing two 113 amino acid chains.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Immune System; Inflammation; Proliferation; Wound Healing; Allergy
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.