Customer Service: (855) 848-6626 | 8:00 a.m - 4:30 p.m. PST | Receive free US shipping in May!

Recombinant Mouse IL-36RA (Carrier-free)
  • Recombinant Mouse IL-36RA (Carrier-free)

Recombinant Mouse IL-36RA (Carrier-free)

Cat No. Size Price Quantity
21-9227-U005 5 µg $70.00
21-9227-U025 25 µg $180.00
21-9227-U100 100 µg $569.00
21-9227-U250 250 µg $999.00
21-9227-U500 500 µg $1,700.00
21-9227-M001 1 mg $2,900.00
Lead time: 2-3 business days

Description

IL-36 Receptor Antagonist (IL-36RA, also known as IL-1F5) belongs to the IL-1 family of cytokines. IL-36 RA is involved in innate immunity and anti-inflammatory responses. IL-36Ra attenuates IL-36 cytokine-induced pro-inflammatory cytokine production by bone marrow derived dendritic cells and antagonizes IL-36 cytokine-induced IFN-γ, IL-4, and IL-17 production in CD4+ T cells. Recombinant Mouse IL-36RA is an E.coli-derived 16.9 kDa protein containing 154 amino acid residues.
View More
IL-36 Receptor Antagonist (IL-36RA, also known as IL-1F5) belongs to the IL-1 family of cytokines. IL-36 RA is involved in innate immunity and anti-inflammatory responses. IL-36Ra attenuates IL-36 cytokine-induced pro-inflammatory cytokine production by bone marrow derived dendritic cells and antagonizes IL-36 cytokine-induced IFN-γ, IL-4, and IL-17 production in CD4+ T cells. Recombinant Mouse IL-36RA is an E.coli-derived 16.9 kDa protein containing 154 amino acid residues.
Hide

Product Details

Name Recombinant Mouse IL-36RA (Carrier-free)
Cat. No. 21-9227
Alternative Names Interleukin-36RA, FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta
Amino Acid Sequence VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Measured by its ability to inhibit secretion of IL-8 by A431 cells in the presence of human IL-36γ.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass 16.9 kDa
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Cancer, Diabetes/Weight Regulation, Immune System, Inflammation, Neurobiology, Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.