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Recombinant Mouse IL-22 (Carrier-free)
  • Recombinant Mouse IL-22 (Carrier-free)

Recombinant Mouse IL-22 (Carrier-free)

Cat No. Size Price Quantity
21-8221-U002 2 µg $69.00
21-8221-U010 10 µg $195.00
21-8221-U100 100 µg $990.00
21-8221-U500 500 µg $2,844.00

Description

IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. IL-22 is produced by activated dendritic cells and T lymphocytes. IL-22 signals through a receptor system consisting of IL-10R-beta, CRF2-4 and IL-22R.
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IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. IL-22 is produced by activated dendritic cells and T lymphocytes. IL-22 signals through a receptor system consisting of IL-10R-beta, CRF2-4 and IL-22R.
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Product Details

Name Recombinant Mouse IL-22 (Carrier-free)
Cat. No. 21-8221
Alternative Names IL-TIF
Amino Acid Sequence MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Assay#1: Determined by its ability to activate STAT following receptor ligand interaction.
Assay#2: Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The expected ED
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse IL-22 is a 33.4 kDa non-disulfide-linked homodimeric protein composed of two 146 amino acid polypeptide chains.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Immune System
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.