Recombinant Mouse IL-17A (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8171-U005 | 5 µg | $105.00 | ||
| 21-8171-U025 | 25 µg | $199.00 | ||
| 21-8171-U100 | 100 µg | $510.00 | ||
| 21-8171-U500 | 500 µg | $1,500.00 |
Technical Data Sheet
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IL-17A is a member of the IL-17 family of cytokines and plays an important role in anti-bacterial responses. IL-17A exists as either a homodimer or as a heterodimer with IL-17F. Elevated levels of IL-17A are associated with several autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, psoriasis, and asthma.
IL-17A is a member of the IL-17 family of cytokines and plays an important role in anti-bacterial responses. IL-17A exists as either a homodimer or as a heterodimer with IL-17F. Elevated levels of IL-17A are associated with several autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, psoriasis, and asthma.
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Product Details
| Name | Recombinant Mouse IL-17A (Carrier-free) |
|---|---|
| Cat. No. | 21-8171 |
| Alternative Names | CTLA-8, IL-17 |
| Amino Acid Sequence | AAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Measured by its ability to induce IL-6 production by NIH 3T3 cells. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Mouse IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Mouse |
| Research Areas | AIDS/HIV; Angiogenesis/Cardiovascular; Immune System?;? Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.