Recombinant Mouse IL-13 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8131-U002 | 2 µg | $61.00 | ||
| 21-8131-U010 | 10 µg | $175.00 | ||
| 21-8131-U100 | 100 µg | $1,050.00 | ||
| 21-8131-U500 | 500 µg | $2,560.00 |
Technical Data Sheet
Request Custom/BulkDescription
IL-13, produced primarily by Th2 cells and to a lesser extent by mast and NK cells, is an immunoregulatory cytokine. Its various functions include induction of matrix metalloproteinases, IgE secretion from activated B cells, inhibition of the expression of inflammatory cytokines including IL-1?, TNF-alpha, IL-6 and IL-8, and enhancement of B cell proliferation.
Recent Citations:
Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM and MacLeod AS. 2017. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. doi: 10.4049/jimmunol.1700739.
IL-13, produced primarily by Th2 cells and to a lesser extent by mast and NK cells, is an immunoregulatory cytokine. Its various functions include induction of matrix metalloproteinases, IgE secretion from activated B cells, inhibition of the expression of inflammatory cytokines including IL-1?, TNF-alpha, IL-6 and IL-8, and enhancement of B cell proliferation.
Recent Citations:
Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM and MacLeod AS. 2017. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. doi: 10.4049/jimmunol.1700739.
» View on Journal of Immunology
HideProduct Details
| Name | Recombinant Mouse IL-13 (Carrier-free) |
|---|---|
| Cat. No. | 21-8131 |
| Alternative Names | P600 |
| Amino Acid Sequence | MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of ≥≥>2.5 x 105 units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Mouse IL-13 is a 12.3 kDa protein composed of 111 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Mouse |
| Research Areas | AIDS/HIV; Cancer; Immune System; Inflammation; Stem Cells & Differentiation; Allergy |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.