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Recombinant Mouse IL-12 p40 (Carrier-free)
  • Recombinant Mouse IL-12 p40 (Carrier-free)

Recombinant Mouse IL-12 p40 (Carrier-free)

Cat No. Size Price Quantity
21-9225-U002 2 µg $70.00
21-9225-U010 10 µg $170.00
21-9225-U050 50 µg $600.00
21-9225-U100 100 µg $950.00
21-9225-U250 250 µg $1,750.00
21-9225-U500 500 µg $3,050.00
21-9225-M001 1 mg (2 x 500 µg) $4,900.00
Lead time: 2-3 business days

Description

Interleukin 12 (IL-12) is produced by activated antigen-presenting cells and is secreted as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD (p35) and 40 kD (p40) subunits. It promotes the development of Th1 responses and is a powerful inducer of IFNγ production by T and NK cells. Recombinant Mouse IL-12 p40 is a 40.0 kDa protein consisting of 313 amino acid residues.
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Interleukin 12 (IL-12) is produced by activated antigen-presenting cells and is secreted as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD (p35) and 40 kD (p40) subunits. It promotes the development of Th1 responses and is a powerful inducer of IFNγ production by T and NK cells. Recombinant Mouse IL-12 p40 is a 40.0 kDa protein consisting of 313 amino acid residues.
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Product Details

Name Recombinant Mouse IL-12 p40 (Carrier-free)
Cat. No. 21-9225
Alternative Names Interleukin-12, NKSF, CTL Maturation Factor (TCMF), Cytotoxic Lymphocyte Maturation Factor (CLMF), TSF, p40:Interleukin-12 subunit beta, IL-12 subunit p40, IL-12B, Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40), NK cell Stimulating Factor Chain 2
Amino Acid Sequence MWELEKDVYV VEVDWTPDAP GETVNLTCDT PEEDDITWTS DQRHGVIGSG KTLTITVKEF LDAGQYTCHK GGETLSHSHL LLHKKENGIW STEILKNFKN KTFLKCEAPN YSGRFTCSWL VQRNMDLKFN IKSSSSSPDS RAVTCGMASL SAEKVTLDQR DYEKYSVSCQ EDVTCPTAEE TLPIELALEA RQQNKYENYS TSFFIRDIIK PDPPKNLQMK PLKNSQVEVS WEYPDSWSTP HSYFSLKFFV RIQRKKEKMK ETEEGCNQKG AFLVEKTSTE VQCKGGNVCV QAQDRYYNSS CSKWACVPCR VRS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to inhibit the proliferative effect of 2 ng/ml mIL-12p70 in T cell-enriched PBMCs.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass 40 kDa
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HEK293
Reactivity Mouse
Research Areas Angiogenesis/Cardiovascular, Allergy, Apoptosis, Cancer, COVID-19, Immune System, Inflammation, Neurobiology, Stem Cells & Differentiation, Transplantation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.