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Recombinant Mouse IGF-I (Carrier-Free)
  • Recombinant Mouse IGF-I (Carrier-Free)

Recombinant Mouse IGF-I (Carrier-Free)

Cat No. Size Price Quantity
21-9137-U010 10 µg $80.00
21-9137-U050 50 µg $195.00
21-9137-U100 100 µg $280.00
21-9137-U500 500 µg $840.00

Description

The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissuein vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin.
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The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissuein vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin.
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Product Details

Name Recombinant Mouse IGF-I (Carrier-Free)
Cat. No. 21-9137
Alternative Names Insulin-like Growth Factor-I, Somatamedin C, IGF-IA
Amino Acid Sequence GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined a cell proliferation assay using FDC-P1 cells is ? 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse IGF-I is a 7.6 kDa globular protein containing amino acids including 3 intra-molecular disulfide bonds.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Inflammation, Proliferation, Wound Healing, Angiogenesis/Cardiovascular, Bone, Skeletal, Cartilage, Diabetes/Weight Regulation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.