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Recombinant Mouse GM-CSF (Carrier-free)
  • Recombinant Mouse GM-CSF (Carrier-free)

Recombinant Mouse GM-CSF (Carrier-free)

Cat No. Size Price Quantity
21-8331-U005 5 µg $56.00
21-8331-U020 20 µg $152.00
21-8331-U100 100 µg $620.00
21-8331-U500 500 µg $1,696.00

Description

Granulocyte macrophage colony stimulating factor, GM-CSF, is a cytokine secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts, and acts as a white blood cell growth factor. GM-CSF also induces stem cells to produce granulocytes and monocytes.

Recent Publications:

Alpdundar Bulut E, Bayyurt Kocabas B, Yazar V, Aykut G, Guler U, Salih B, Surucu Yilmaz N, Ayanoglu IC, Polat MM, Akcali KC, Gursel I, Gursel M. Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells. J Immunol. 2020 Oct 7:ji2000731. doi: 10.4049/jimmunol.2000731. PMID: 33028617. 

» View on Journal of Immunology

Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM and MacLeod AS. 2017. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. doi: 10.4049/jimmunol.1700739.

» View on Journal of Immunology





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Granulocyte macrophage colony stimulating factor, GM-CSF, is a cytokine secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts, and acts as a white blood cell growth factor. GM-CSF also induces stem cells to produce granulocytes and monocytes.

Recent Publications:

Alpdundar Bulut E, Bayyurt Kocabas B, Yazar V, Aykut G, Guler U, Salih B, Surucu Yilmaz N, Ayanoglu IC, Polat MM, Akcali KC, Gursel I, Gursel M. Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells. J Immunol. 2020 Oct 7:ji2000731. doi: 10.4049/jimmunol.2000731. PMID: 33028617. 

» View on Journal of Immunology

Suwanpradid J, Shih M, Pontius L, Yang B, Birukova A, Guttman-Yassky E, Corcoran DL, Que LG, Tighe RM and MacLeod AS. 2017. Arginase1 Deficiency in Monocytes/Macrophages Upregulates Inducible Nitric Oxide Synthase To Promote Cutaneous Contact Hypersensitivity. J Immunol. doi: 10.4049/jimmunol.1700739.

» View on Journal of Immunology





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Product Details

Name Recombinant Mouse GM-CSF (Carrier-free)
Cat. No. 21-8331
Alternative Names
Amino Acid Sequence MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse GM-CSF is a 14.2 kDa protein composed of 125 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Cancer; Cell Culture; Inflammation; Proliferation; Stem Cells & Differentiation; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.