Recombinant Mouse G-CSF (Carrier-free)
  • Recombinant Mouse G-CSF (Carrier-free)

Recombinant Mouse G-CSF (Carrier-free)

Cat No. Size Price Quantity
21-8301-U002 2 µg $66.00
21-8301-U010 10 µg $185.00
21-8301-U100 100 µg $975.00
21-8301-U500 500 µg $2,993.00
Lead time: 2-3 business days

Description

Mouse G-CSF is a hematopoietic growth factor that drives differentiation of stem cells and lineage committed progenitor cells to neutrophils and enhances their functional activities. It is produced by a variety of cell types including macrophages, endothelial cells, fibroblasts, and bone marrow stroma. Human G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. G-CSF alone does not appear to act directly on already mobilized cells although it is an important inducer of mobilization from bone marrow into the blood stream for HSCs.
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Mouse G-CSF is a hematopoietic growth factor that drives differentiation of stem cells and lineage committed progenitor cells to neutrophils and enhances their functional activities. It is produced by a variety of cell types including macrophages, endothelial cells, fibroblasts, and bone marrow stroma. Human G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. G-CSF alone does not appear to act directly on already mobilized cells although it is an important inducer of mobilization from bone marrow into the blood stream for HSCs.
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Product Details

Name Recombinant Mouse G-CSF (Carrier-free)
Cat. No. 21-8301
Alternative Names Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFb, pluripoietin
Amino Acid Sequence MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity ED50 ≤ 0.05 ng/ml - determined by dose-dependent stimulation of the proliferation of Mouse NFS-60 cells corresponding to a specific activity of ≥ 2 x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse G-CSF is a 19.0 kDa protein composed of 179 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas AIDS/HIV; Angiogenesis/Cardiovascular; Cancer; Diabetes / Weight Regulation; Inflammation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.