Recombinant Mouse FLT3 Ligand (Carrier-free)
  • Recombinant Mouse FLT3 Ligand (Carrier-free)

Recombinant Mouse FLT3 Ligand (Carrier-free)

Cat No. Size Price Quantity
21-8001-U002 2 µg $54.00
21-8001-U010 10 µg $134.00
21-8001-U100 100 µg $725.00
Lead time: 2-3 business days

Description

FLT3 ligand acts upon hematopoietic precursors including stem cells. FLT3 ligand along with other Colony Stimulating Factors such as G-CSF or GM-CSF have critical functions as drivers of DC expansion and maturation and also appear to expand specific DC subsets. FLT3 ligand also acts in expansion and mobilization of DCs as well as enhancing both B and T cell numbers and activity. FLT3 ligand acts in conjunction with other CSFs and interleukins to induce growth and differentiation but does not independently stimulate proliferation of early hematopoitic cells. FLT3 ligand has no activity on mast cells.
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FLT3 ligand acts upon hematopoietic precursors including stem cells. FLT3 ligand along with other Colony Stimulating Factors such as G-CSF or GM-CSF have critical functions as drivers of DC expansion and maturation and also appear to expand specific DC subsets. FLT3 ligand also acts in expansion and mobilization of DCs as well as enhancing both B and T cell numbers and activity. FLT3 ligand acts in conjunction with other CSFs and interleukins to induce growth and differentiation but does not independently stimulate proliferation of early hematopoitic cells. FLT3 ligand has no activity on mast cells.
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Product Details

Name Recombinant Mouse FLT3 Ligand (Carrier-free)
Cat. No. 21-8001
Alternative Names Fms-related tyrosine kinase 3 ligand
Amino Acid Sequence MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Assessed by stimulation of the proliferation of human AML5 cells.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse FLT3 Ligand is a soluble 18.6 kDa protein composed of 163 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Cancer; Cell Culture; Immune System; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.