Recombinant Mouse FGF-basic (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7049-U010 | 10 µg | $76.00 | ||
| 21-7049-U050 | 50 µg | $155.00 | ||
| 21-7049-U100 | 100 µg | $265.00 | ||
| 21-7049-U500 | 500 µg | $760.00 |
Technical Data Sheet
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The Fibroblast Growth Factors (FGFs) are a large family of proteins that play a key role in many aspects of development and differentiation of a variety of tissues. FGF-basic is expressed in most types of tissue and plays a role in normal development and wound healing as well as neoplastic transformation. The functional activities of FGF-basic are mediated by receptor tyrosine kinases and modulated by heparin sulfate.
The Fibroblast Growth Factors (FGFs) are a large family of proteins that play a key role in many aspects of development and differentiation of a variety of tissues. FGF-basic is expressed in most types of tissue and plays a role in normal development and wound healing as well as neoplastic transformation. The functional activities of FGF-basic are mediated by receptor tyrosine kinases and modulated by heparin sulfate.
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Product Details
| Name | Recombinant Mouse FGF-basic (Carrier-free) | |
|---|---|---|
| Cat. No. | 21-7049 | |
| Alternative Names | Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin | |
| Amino Acid Sequence | PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS | |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). | |
| Bioactivity | Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥≥≤ 1 x 10Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Mouse FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues. | |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. | |
| Purity (%) | 95 | |
| Source | E. coli | |
| Reactivity | Mouse | |
| Research Areas | Angiogenesis/Cardiovascular; Cancer; Cell Culture; FGF Superfamily; Inflammation; Neurobiology; Proliferation; Stem Cells & Differentiation; Wound Healing | |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. | |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.