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Recombinant Mouse FGF-23 (Carrier-Free)
  • Recombinant Mouse FGF-23 (Carrier-Free)

Recombinant Mouse FGF-23 (Carrier-Free)

Cat No. Size Price Quantity
21-9210-U005 5 µg $80.00
21-9210-U020 20 µg $195.00
21-9210-U100 100 µg $780.00
21-9210-U500 500 µg $2,340.00

Description

The FGF family plays a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism.
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The FGF family plays a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism.
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Product Details

Name Recombinant Mouse FGF-23 (Carrier-Free)
Cat. No. 21-9210
Alternative Names Fibroblast Growth Factor-23
Amino Acid Sequence MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to stimulate the proliferation of Mouse NIH-3T3 cells. The expected ED50 for this effect is 0.3-0.5 ug/ml, in the presence of Mouse Klotho and heparin.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Source E. coli
Reactivity Mouse
Research Areas Proliferation, Stem Cells & Differentiation, Angiogenesis/Cardiovascular, Bone, Skeletal, Cartilage, FGF Superfamily
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.