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Recombinant Mouse CCL2 (MCP-1) (Carrier-free)
  • Recombinant Mouse CCL2 (MCP-1) (Carrier-free)

Recombinant Mouse CCL2 (MCP-1) (Carrier-free)

Cat No. Size Price Quantity
21-8152-U002 2 µg $73.00
21-8152-U010 10 µg $195.00
21-8152-U100 100 µg $570.00
21-8152-U500 500 µg $1,671.00

Description

Monocyte chemotactic protein-1, MCP-1, also known as Chemokine (C-C motif) ligand 2, CCL2, is a member of the CC chemokine family and is expressed in endothelial cells, smooth muscle cells, and monocytes. At sites of inflamation MCP-1 is known to recruit monocytes, memory T cells and dendritic cells. MCP-1 is implicated in the pathogenisis of psoriasis, rheumatoid arthritis and atherosclerosis.
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Monocyte chemotactic protein-1, MCP-1, also known as Chemokine (C-C motif) ligand 2, CCL2, is a member of the CC chemokine family and is expressed in endothelial cells, smooth muscle cells, and monocytes. At sites of inflamation MCP-1 is known to recruit monocytes, memory T cells and dendritic cells. MCP-1 is implicated in the pathogenisis of psoriasis, rheumatoid arthritis and atherosclerosis.
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Product Details

Name Recombinant Mouse CCL2 (MCP-1) (Carrier-free)
Cat. No. 21-8152
Alternative Names Monocyte Chemotactic Protein-1, CCL2, MCAF, JE
Amino Acid Sequence QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Mouse MCP-1 (CCL2) is a 13.8 kDa protein containing 125 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Mouse
Research Areas Angiogenesis/Cardiovascular; Cancer; Chemotaxis; Immune System; Inflammation; Neurobiology; Wound Healing; Allergy
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.