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Recombinant Human WNT-7A (Carrier-free)
  • Recombinant Human WNT-7A (Carrier-free)

Recombinant Human WNT-7A (Carrier-free)

Cat No. Size Price Quantity
21-8694-U003 3 µg $76.00
21-8694-U015 15 µg $175.00

Description

Wnt-7a is a secreted member of the Wingless-type MMTV integration site (Wnt) family of signaling molecules that play a role in patterning, cell-cell communication and cell fate. It is expressed in placenta, kidney, testis, uterus, fetal lung and fetal and adult brain. Wnt-7a can modulate the development of the uterus, cerebellum and limbs, and signals transduced through Wnt-7a and its receptors are found to be critical for the development of oviduct and uterus in females. Wnt proteins can signal through the Frizzled family of receptors and co-receptors LRP5/6 (low-density lipoprotein-related receptor proteins 5 and 6), termed the Wnt canonical pathway.
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Wnt-7a is a secreted member of the Wingless-type MMTV integration site (Wnt) family of signaling molecules that play a role in patterning, cell-cell communication and cell fate. It is expressed in placenta, kidney, testis, uterus, fetal lung and fetal and adult brain. Wnt-7a can modulate the development of the uterus, cerebellum and limbs, and signals transduced through Wnt-7a and its receptors are found to be critical for the development of oviduct and uterus in females. Wnt proteins can signal through the Frizzled family of receptors and co-receptors LRP5/6 (low-density lipoprotein-related receptor proteins 5 and 6), termed the Wnt canonical pathway.
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Product Details

Name Recombinant Human WNT-7A (Carrier-free)
Cat. No. 21-8694
Alternative Names
Amino Acid Sequence LGASIICNKI PGLAPRQRAI CQSRPDAIIV IGEGSQMGLD ECQFQFRNGR WNCSALGERT VFGKELKVGS REAAFTYAII AAGVAHAITA ACTQGNLSDC GCDKEKQGQY HRDEGWKWGG CSADIRYGIG FAKVFVDARE IKQNARTLMN LHNNEAGRKI LEENMKLECK CHGVSGSCTT KTCWTTLPQF RELGYVLKDK YNEAVHVEPV RASRNKRPTF LKIKKPLSYR KP
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human Wnt-7a is a 35.5 kDa glycoprotein containing 318 amino acids. Due to glycosylation, Wnt-7a migrates between ≥ ≥ ≥ 40-55 kDa by SDS-PAGE gel under unreduced conditions.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 80
Source HEK293 cells
Reactivity Human
Research Areas Cancer; Inflammation; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.