Recombinant Human VAP-1 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7090-U002 | 2 µg | $76.00 | ||
| 21-7090-U010 | 10 µg | $175.00 | ||
| 21-7090-U100 | 100 µg | $1,025.00 | ||
| 21-7090-U500 | 500 µg | $3,100.00 |
Lead time: 2-3 business days
Technical Data Sheet
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Vascular adhesion protein1 (VAP1) is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family and functions both as an enzyme and an adhesion molecule for lymphocytes. VAP-1 is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues.
Vascular adhesion protein1 (VAP1) is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family and functions both as an enzyme and an adhesion molecule for lymphocytes. VAP-1 is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues.
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Product Details
| Name | Recombinant Human VAP-1 (Carrier-free) |
|---|---|
| Cat. No. | 21-7090 |
| Alternative Names | Vascular Adhesion Protein-1, AOC3, SSAO, HPAO, Copper Amine Oxidase, Membrane Primary Amine Oxidase |
| Amino Acid Sequence | GRGGDGGEPS QLPHCPSVSP SAQPWTHPGQ SQLFADLSRE ELTAVMRFLT QRLGPGLVDA AQARPSDNCV FSVELQLPPK AAALAHLDRG SPPPAREALA IVFFGRQPQP NVSELVVGPL PHPSYMRDVT VERHGGPLPY HRRPVLFQEY LDIDQMIFNR ELPQASGLLH HCCFYKHRGR NLVTMTTAPR GLQSGDRATW FGLYYNISGA GFFLHHVGLE LLVNHKALDP AR |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Measured by its ability to produce hydrogen peroxide during the oxidation of benzylamine. The specific activity >16 pMoles/min/µg of VAP-1. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant VAP-1 is a mixture of monomeric and disulfide linked homodimeric forms of a 737 amino acid polypeptide corresponding to amino acids 27 to 763 of the VAP-1 precursor. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | CHO cells |
| Reactivity | Human |
| Research Areas | Angiogenesis/Cardiovascular; Cancer; Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.