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Recombinant Human TSLP (Carrier-free)
  • Recombinant Human TSLP (Carrier-free)

Recombinant Human TSLP (Carrier-free)

Cat No. Size Price Quantity
21-8497-U002 2 µg $76.00
21-8497-U010 10 µg $175.00
21-8497-U100 100 µg $945.00

Description

Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic cytokine that shares some biological activities with IL-7. It is found in many tissues, but has highest expression in heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex comprised of the IL-7Ralpha (CD127) and the TSLPR. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP promotes Th2 responses and has been associated with the development of allergic disorders in humans, such as asthma, atopic dermatitis, and food allergies.
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Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic cytokine that shares some biological activities with IL-7. It is found in many tissues, but has highest expression in heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex comprised of the IL-7Ralpha (CD127) and the TSLPR. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP promotes Th2 responses and has been associated with the development of allergic disorders in humans, such as asthma, atopic dermatitis, and food allergies.
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Product Details

Name Recombinant Human TSLP (Carrier-free)
Cat. No. 21-8497
Alternative Names Thymic Stromal Lymphopoietin
Amino Acid Sequence MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPTAGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGLWRRFNRPLLK QQ
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Data not available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human TSLP is a 15.0 kDa protein consisting of 132 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Apoptosis; Inflammation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.