Recombinant Human TSLP (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8497-U002 | 2 µg | $76.00 | ||
| 21-8497-U010 | 10 µg | $175.00 | ||
| 21-8497-U100 | 100 µg | $945.00 |
Technical Data Sheet
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Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic cytokine that shares some biological activities with IL-7. It is found in many tissues, but has highest expression in heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex comprised of the IL-7Ralpha (CD127) and the TSLPR. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP promotes Th2 responses and has been associated with the development of allergic disorders in humans, such as asthma, atopic dermatitis, and food allergies.
Thymic Stromal Lymphopoietin (TSLP) is a hemopoietic cytokine that shares some biological activities with IL-7. It is found in many tissues, but has highest expression in heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex comprised of the IL-7Ralpha (CD127) and the TSLPR. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP promotes Th2 responses and has been associated with the development of allergic disorders in humans, such as asthma, atopic dermatitis, and food allergies.
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Product Details
| Name | Recombinant Human TSLP (Carrier-free) |
|---|---|
| Cat. No. | 21-8497 |
| Alternative Names | Thymic Stromal Lymphopoietin |
| Amino Acid Sequence | MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPTAGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGLWRRFNRPLLK QQ |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Data not available at this time. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human TSLP is a 15.0 kDa protein consisting of 132 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Apoptosis; Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.