

Recombinant Human TLR-3 (Carrier-free)
Cat No. | Size | Price | Quantity | |
---|---|---|---|---|
21-7087-U005 | 5 µg | $76.00 | ||
21-7087-U025 | 25 µg | $175.00 | ||
21-7087-U100 | 100 µg | $585.00 | ||
21-7087-U500 | 500 µg | $1,795.00 |
Description
Product Details
Name | Recombinant Human TLR-3 (Carrier-free) |
---|---|
Cat. No. | 21-7087 |
Alternative Names | Toll-like receptor 3, CD283 antigen |
Amino Acid Sequence | STTKCTVSHE VADCSHLKLT QVPDDLPTNI TVLNLTHNQL RRLPAANFTR YSQLTSLDVG FNTISKLEPE LCQKLPMLKV LNLQHNELSQ LSDKTFAFCT NLTELHLMSN SIQKIKNNPF VKQKNLITLD LSHNGLSSTK LGTQVQLENL QELLLSNNKI QALKSEELDI FANSSLKKLEL SSNQIKEFSP GCFHAIGRLF GLFLNNVQLG PSLTEKLCLE LANTSIRNLS L |
Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Bioactivity | Determined by its ability to inhibit IL-8 secretion induced by Poly I:C in the TLR3 receptor-expressing HEK293 cells (HEK293 TLR3r). The ED50for this effect is ≥ 30 µg/ml in the presence of 100 µg/ml of Poly I:C. |
Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
Molecular Mass | Recombinant human TLR-3 is 77.4 kDa glycoprotein containing 681 residues which comprise the TLR-3 extracellular domain. |
Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Purity (%) | 95 |
Source | HEK293 cells |
Reactivity | Human |
Research Areas | Apoptosis; Inflammation; Receptors |
Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
Application | Bioassay |
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.