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Recombinant Human TGF-ß3 (Carrier-free)
  • Recombinant Human TGF-ß3 (Carrier-free)

Recombinant Human TGF-ß3 (Carrier-free)

Cat No. Size Price Quantity
21-8370-U002 2 µg $80.00
21-8370-U010 10 µg $227.00
21-8370-U100 100 µg $1,025.00

Description

TGF-beta3 is a member of the TGF family of cytokines. TGF beta3 is secreted as a precursor protein that is cleaved to produce an N-terminal latency-associated (LAP) peptide and a C-terminal mature TGF-beta that contains the biological activity of ≥≥the cytokine. TGF-beta3 is involved in embryogenesis and cell differentiation.
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TGF-beta3 is a member of the TGF family of cytokines. TGF beta3 is secreted as a precursor protein that is cleaved to produce an N-terminal latency-associated (LAP) peptide and a C-terminal mature TGF-beta that contains the biological activity of ≥≥the cytokine. TGF-beta3 is involved in embryogenesis and cell differentiation.
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Product Details

Name Recombinant Human TGF-β3(Carrier-free)
Cat. No. 21-8370
Alternative Names Transforming Growth Factor-beta 3
Amino Acid Sequence ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined by TGF-beta3's ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥2 x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human TGF-beta3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Apoptosis; Cancer; Immune System; Inflammation; Proliferation; Stem Cells & Differentiation; TGF-β Superfamily; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.