Recombinant Human TACI (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7158-U005 | 5 µg | $76.00 | ||
| 21-7158-U020 | 20 µg | $179.00 | ||
| 21-7158-U100 | 100 µg | $800.00 | ||
| 21-7158-U500 | 500 µg | $2,995.00 |
Technical Data Sheet
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TACI (Transmembrane activator and CAML interactor) is a member of the TNF-α receptor superfamily. Similar to the related BCMA protein, it binds both APRIL and BAFF (BLyS) to mediate NKF-kappaB responses. It is expressed by mature B lymphocytes and plays an important role in positive regulation of B cell growth and antibody production. TACI supports survival of activated B cells and plasmablasts in vitro.
TACI (Transmembrane activator and CAML interactor) is a member of the TNF-α receptor superfamily. Similar to the related BCMA protein, it binds both APRIL and BAFF (BLyS) to mediate NKF-kappaB responses. It is expressed by mature B lymphocytes and plays an important role in positive regulation of B cell growth and antibody production. TACI supports survival of activated B cells and plasmablasts in vitro.
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Product Details
| Name | Recombinant Human TACI (Carrier-free) |
|---|---|
| Cat. No. | 21-7158 |
| Alternative Names | TNFRSF13B, CD267, Transmembrane activator and CAML interactor |
| Amino Acid Sequence | SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Within a concentration range of 1.0-3.0 μg/ml, its ability to block human BAFF-induced T2B cell survival is determined. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human TACI is a 17.8 kDa protein consisting of 159 amino acids that correspond to the cysteine-rich extracellular domain. |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | TNF-α Superfamily, Immune System, Cancer, Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.