Customer Service: (855) 848-6626 | 8:00 a.m - 4:30 p.m. PST | Receive a Free Mask with Orders over $300

Recombinant Human sCD34 (Carrier-free)
  • Recombinant Human sCD34 (Carrier-free)

Recombinant Human sCD34 (Carrier-free)

Cat No. Size Price Quantity
21-7174-U005 5 µg $76.00
21-7174-U020 20 µg $175.00
21-7174-U100 100 µg $585.00
21-7174-U500 500 µg $1,750.00

Description

CD34 is a type I monomeric sialomucin-like glycophophoprotein that is highly glycosylated and phosphorylated by protein kinase C. As CD34 protein is selectively expressed on hematopoietic progenitor cells it is extensively used as a molecular marker for identification, isolation and manipulation of hemopoietic stem cells and progenitors. The CD34 protein may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, and by vascular endothelia in the adult. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
View More
CD34 is a type I monomeric sialomucin-like glycophophoprotein that is highly glycosylated and phosphorylated by protein kinase C. As CD34 protein is selectively expressed on hematopoietic progenitor cells it is extensively used as a molecular marker for identification, isolation and manipulation of hemopoietic stem cells and progenitors. The CD34 protein may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, and by vascular endothelia in the adult. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
Hide

Product Details

Name Recombinant Human sCD34 (Carrier-free)
Cat. No. 21-7174
Alternative Names soluble CD34, Hematopoietic progenitor cell antigen CD34
Amino Acid Sequence LDNNGTATPE LPTQGTFSNV STNVSYQETT TPSTLGSTSL HPVSQHGNEA TTNITETTVK FTSTSVITSV YGNTNSSVQS QTSVISTVFT TPANVSTPET TLKPSLSPGN VSDLSTTSTS LATSPTKPYT SSSPILSDIK AEIKCSGIRE VKLTQGICLE QNKTSSCAEF KKDRGEGLAR VLCGEEQADA DAGAQVCSLL LAQSEVRPQC LLLVLANRTE ISSKLQLMKK HQ
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Testing in Progress.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein. The calculated molecular weight of Recombinant Human sCD34 is 27.4 kDa.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source CHO cells
Reactivity Human
Research Areas
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.