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Recombinant Human Relaxin-3 (INSL7) (Carrier-free)
  • Recombinant Human Relaxin-3 (INSL7) (Carrier-free)

Recombinant Human Relaxin-3 (INSL7) (Carrier-free)

Cat No. Size Price Quantity
21-7129-U005 5 µg $76.00
21-7129-U025 25 µg $175.00
21-7129-U100 100 µg $585.00
21-7129-U500 500 µg $1,750.00

Description

At least seven relaxin-like proteins make up the Insulin/Relaxin superfamily. Most consist of two peptide subunits, an alpha-chain and a beta-chain, linked by disulfide bonds. Relaxin-3, also known as INSL7, has been reported as a ligand for LGR7 (RXFP1), and is the only known ligand for GPCR135 (RXFP3). It binds less often with GPCR142. Relaxin-3 is a secreted protein that is reported to play a role in stress response. It is almost exclusively expressed within the brain stem.
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At least seven relaxin-like proteins make up the Insulin/Relaxin superfamily. Most consist of two peptide subunits, an alpha-chain and a beta-chain, linked by disulfide bonds. Relaxin-3, also known as INSL7, has been reported as a ligand for LGR7 (RXFP1), and is the only known ligand for GPCR135 (RXFP3). It binds less often with GPCR142. Relaxin-3 is a secreted protein that is reported to play a role in stress response. It is almost exclusively expressed within the brain stem.
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Product Details

Name Recombinant Human Relaxin-3 (INSL7) (Carrier-free)
Cat. No. 21-7129
Alternative Names H3 relaxin, Insulin-like peptide-7, INSL7, RNX3, RLN3
Amino Acid Sequence

alpha chain: DVLAGLSSSC CKWGCSKSEI SSLC

beta chain: RAAPYGVRLC GREFIRAVIF TCGGSRW

Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity No data available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Relaxin-3 is a heterodimeric protein of ≥ 5.5 kDa, consisting of a 24 amino acid alpha-chain and a 27 amino acid beta-chain.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Diabetes, Lipid Metabolism, Neurobiology
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.