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Recombinant Human Relaxin-2 (Carrier-Free)
  • Recombinant Human Relaxin-2 (Carrier-Free)

Recombinant Human Relaxin-2 (Carrier-Free)

Cat No. Size Price Quantity
21-9092-U005 5 µg $80.00
21-9092-U025 25 µg $195.00
21-9092-U100 100 µg $600.00
21-9092-U500 500 µg $1,800.00

Description

Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and ovaries during pregnancy. Of the three known relaxin genes, relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as “orphan” G protein-coupled receptors. Signaling by relaxin-2 through its target receptors enhances the growth of pubic ligaments, and the ripening of the cervix during birth.
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Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and ovaries during pregnancy. Of the three known relaxin genes, relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as “orphan” G protein-coupled receptors. Signaling by relaxin-2 through its target receptors enhances the growth of pubic ligaments, and the ripening of the cervix during birth.
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Product Details

Name Recombinant Human Relaxin-2 (Carrier-Free)
Cat. No. 21-9092
Alternative Names H2 relaxin, RLN2
Amino Acid Sequence A-Chain:QLYSALANKC CHVGCTKRSL ARFC B-Chain:DSWMEEVIKL CGRELVRAQI AICGMSTWS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Data not available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Relaxin-2 is a non-glycosylated, 6.0 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain, and a 29 amino acid B-chain.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E.coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.