Recombinant Human Prolactin (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7124-U010 | 10 µg | $69.00 | ||
| 21-7124-U050 | 50 µg | $165.00 | ||
| 21-7124-U100 | 100 µg | $270.00 | ||
| 21-7124-U500 | 500 µg | $859.00 |
Technical Data Sheet
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Prolactin is a globular, secreted neuroendocrine pituitary hormone present as both glycosylated and non-glycosylated monomers. The non-glycoslyated form is expressed in the pituitary gland and stored in granules prior to being secreted. The glycosylated protein reportedly has lower biologic activity but is constitutively secreted. Prolactin binds the prolactin receptor (PRLR), which has widespread expression. Prolactin is a lactogenic protein, acting mainly on the mammary gland and promoting lactation in females during pregnancy and suckling. It also has been reported to have functions related to immunoregulation, breast and prostate cancer development, and regulation of reproductive function.
Prolactin is a globular, secreted neuroendocrine pituitary hormone present as both glycosylated and non-glycosylated monomers. The non-glycoslyated form is expressed in the pituitary gland and stored in granules prior to being secreted. The glycosylated protein reportedly has lower biologic activity but is constitutively secreted. Prolactin binds the prolactin receptor (PRLR), which has widespread expression. Prolactin is a lactogenic protein, acting mainly on the mammary gland and promoting lactation in females during pregnancy and suckling. It also has been reported to have functions related to immunoregulation, breast and prostate cancer development, and regulation of reproductive function.
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Product Details
| Name | Recombinant Human Prolactin (Carrier-free) |
|---|---|
| Cat. No. | 21-7124 |
| Alternative Names | Mammotropin, Luterotropic hormone, Luteotropin, PRL |
| Amino Acid Sequence | MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Using a concentration range of 0.1-1.0 ng/ml, the ability to induce proliferation of rat Nb2-11 cells is determined. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human Prolactin consists of ≥ 200 amino acids, resulting in a 23.0 kDa protein. |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Differentiation, Proliferation, Neurobiology, Stem Cells |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.