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Recombinant Human PLGF-2 (Carrier-Free)
  • Recombinant Human PLGF-2 (Carrier-Free)

Recombinant Human PLGF-2 (Carrier-Free)

Cat No. Size Price Quantity
21-9049-U005 5 µg $80.00
21-9049-U025 25 µg $195.00
21-9049-U100 100 µg $600.00
21-9049-U500 500 µg $1,800.00

Description

PLGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PLGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin.
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PLGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PLGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin.
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Product Details

Name Recombinant Human PLGF-2 (Carrier-Free)
Cat. No. 21-9049
Alternative Names Placenta Growth Factor 2, PGFL
Amino Acid Sequence LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCCGDAVPRR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract human monocytes of using a concentration range of ≥ 5.0-50.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human PLGF-2 is a 34.0 kDa disulfide-linked homodimeric protein of two 150 amino acid polypeptide chains.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source E.coli
Reactivity Human
Research Areas Inflammation, Proliferation, Cancer, Angiogenesis/Cardiovascular
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.