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Recombinant Human OTOR (Carrier-Free)
  • Recombinant Human OTOR (Carrier-Free)

Recombinant Human OTOR (Carrier-Free)

Cat No. Size Price Quantity
21-9088-U005 5 µg $80.00
21-9088-U020 20 µg $195.00
21-9088-U100 100 µg $780.00
21-9088-U500 500 µg $2,340.00

Description

OTOR, also called Otoraplin and MIAL, is a secreted cytokine of the MIA/OTOR family. Members of this family, which include MIA, MIA2, and TANGO, share a Src homology-3 (SH3)-like domain. OTOR is predominantly expressed in the cochlea of the inner ear, and, to a lesser extent, in fetal brain tissue and some cartilage tissues. OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function.
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OTOR, also called Otoraplin and MIAL, is a secreted cytokine of the MIA/OTOR family. Members of this family, which include MIA, MIA2, and TANGO, share a Src homology-3 (SH3)-like domain. OTOR is predominantly expressed in the cochlea of the inner ear, and, to a lesser extent, in fetal brain tissue and some cartilage tissues. OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function.
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Product Details

Name Recombinant Human OTOR (Carrier-Free)
Cat. No. 21-9088
Alternative Names Otoraplin, MIAL (Melanoma Inhibitory Activity-like, Protein)
Amino Acid Sequence MVHGIFMDRL ASKKLCADDE CVYTISLASA QEDYNAPDCR FINVKKGQQI YVYSKLVKENGAGEFWAGSV YGDGQDEMGV VGYFPRNLVK EQRVYQEATK EVPTTDIDFF CE
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Data not available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human OTOR is a 12.7 kDa globular protein containing 112 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E.coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular, Cancer
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.