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Recombinant Human Oncostatin-M (Carrier-free)
  • Recombinant Human Oncostatin-M (Carrier-free)

Recombinant Human Oncostatin-M (Carrier-free)

Cat No. Size Price Quantity
21-7079-U002 2 µg $69.00
21-7079-U010 10 µg $179.00
21-7079-U100 100 µg $955.00
21-7079-U500 500 µg $3,100.00

Description

Oncostatin M (OSM) is a growth and differentiation factor produced by activated T cells, monocytes and Kaposi’s sarcoma cells. It shares many biological functions with LIF, and belongs to a cytokine family that includes G-CSF, IL-6 and LIF. OSM can promote cytokine production, including IL-6, G-CSF, GM-CSF, in endothelial cells, but may also act as an inhibitor of growth for some normal and tumor cell lines.
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Oncostatin M (OSM) is a growth and differentiation factor produced by activated T cells, monocytes and Kaposi’s sarcoma cells. It shares many biological functions with LIF, and belongs to a cytokine family that includes G-CSF, IL-6 and LIF. OSM can promote cytokine production, including IL-6, G-CSF, GM-CSF, in endothelial cells, but may also act as an inhibitor of growth for some normal and tumor cell lines.
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Product Details

Name Recombinant Human Oncostatin-M (Carrier-free)
Cat. No. 21-7079
Alternative Names OSM
Amino Acid Sequence AAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human Oncostatin M is a 23.6 kDa protein, containing 209 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV; Angiogenesis/Cardiovascular; Bone, Skeletal, Cartilage; Immune System; Inflammation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.