Recombinant Human Oncostatin M (196 a.a.) (Carrier-free)
  • Recombinant Human Oncostatin M (196 a.a.) (Carrier-free)

Recombinant Human Oncostatin M (196 a.a.) (Carrier-free)

Cat No. Size Price Quantity
21-9229-U002 2 µg $70.00
21-9229-U010 10 µg $180.00
21-9229-U050 50 µg $600.00
21-9229-U100 100 µg $950.00
21-9229-U250 250 µg $1,750.00
21-9229-U500 500 µg $3,050.00
21-9229-M001 1 mg $4,900.00
Lead time: 2-3 business days

Description

Oncostatin M (OSM) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. It is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis, and hematopoiesis. OSM can have both stimulatory and inhibitory effects on cell proliferation, depending on the cell type and it also promotes cytokine release from endothelial cells. Recombinant Human Oncostatin M (196 a.a.) is a HEK293 cell-derived, 196 amino-acid length glycoprotein that has a calculated molecular weight of 22.2 kDa, but migrates at an apparent molecular weight of 32-34 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation.
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Oncostatin M (OSM) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. It is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis, and hematopoiesis. OSM can have both stimulatory and inhibitory effects on cell proliferation, depending on the cell type and it also promotes cytokine release from endothelial cells. Recombinant Human Oncostatin M (196 a.a.) is a HEK293 cell-derived, 196 amino-acid length glycoprotein that has a calculated molecular weight of 22.2 kDa, but migrates at an apparent molecular weight of 32-34 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation.
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Product Details

Name Recombinant Human Oncostatin M (196 a.a.) (Carrier-free)
Cat. No. 21-9229
Alternative Names OSM
Amino Acid Sequence AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRR
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass 22.2 kDa
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source HEK293
Reactivity Human
Research Areas AIDS/HIV, Angiogenesis/Cardiovascular, Bone/Skeletal/Cartilage, Immune System, Inflammation, Neurobiology, Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.