Recombinant Human NNT-1 (BCSF-3) (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7074-U002 | 2 µg | $76.00 | ||
| 21-7074-U010 | 10 µg | $175.00 | ||
| 21-7074-U100 | 100 µg | $1,025.00 | ||
| 21-7074-U500 | 500 µg | $3,100.00 |
Technical Data Sheet
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Novel neurotrophin-1 (NNT-1), also known as B cell stimulating factor-3 (BSF-3), is a neurotrophic factor with B-cell stimulating capabilities and belongs to the IL-6 family of cytokines. It is expressed in lymph node and spleen. NNT-1 is a gp130 activator and when associated with the soluble receptor cytokine-like factor-1 (CLF-1) it activates gp130, LIF receptor (LIFR) and STAT3.
Novel neurotrophin-1 (NNT-1), also known as B cell stimulating factor-3 (BSF-3), is a neurotrophic factor with B-cell stimulating capabilities and belongs to the IL-6 family of cytokines. It is expressed in lymph node and spleen. NNT-1 is a gp130 activator and when associated with the soluble receptor cytokine-like factor-1 (CLF-1) it activates gp130, LIF receptor (LIFR) and STAT3.
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Product Details
| Name | Recombinant Human NNT-1 (BCSF-3) (Carrier-free) |
|---|---|
| Cat. No. | 21-7074 |
| Alternative Names | Novel Neurtrophin-1/B-Cell Stimulating Factor-3, Cardiotrophin-like cytokine |
| Amino Acid Sequence | MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/ml. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Diabetes / Weight Regulation; Immune System; Neurobiology |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.