Recombinant Human Neuritin (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7115-U005 | 5 µg | $76.00 | ||
| 21-7115-U020 | 20 µg | $175.00 | ||
| 21-7115-U100 | 100 µg | $585.00 | ||
| 21-7115-U500 | 500 µg | $1,795.00 |
Technical Data Sheet
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Neuritin (NRN1, CPG15) is a highly conserved neurotrophic factor that promotes neurite outgrowth and branching, indicating its role in neuritogenesis. Expression is induced by synaptic activity, as well as by neurotrophins including BDNF, NGF and NT3. In the developing nervous system, Neuritin is expressed in postmitotic-differentiating neurons. In the adult, it is involved in regulating synaptic plasticity.
Neuritin (NRN1, CPG15) is a highly conserved neurotrophic factor that promotes neurite outgrowth and branching, indicating its role in neuritogenesis. Expression is induced by synaptic activity, as well as by neurotrophins including BDNF, NGF and NT3. In the developing nervous system, Neuritin is expressed in postmitotic-differentiating neurons. In the adult, it is involved in regulating synaptic plasticity.
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Product Details
| Name | Recombinant Human Neuritin (Carrier-free) |
|---|---|
| Cat. No. | 21-7115 |
| Alternative Names | CPG15, NRN1, NRN |
| Amino Acid Sequence | AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human Neuritin is a homodimer that consists of two 9.72 kDa polypeptide monomers, made up of 88 amino acids each. |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Neurobiology |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.