Recombinant Human Nesfatin-1 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-7114-U020 | 20 µg | $76.00 | ||
| 21-7114-U100 | 100 µg | $179.00 | ||
| 21-7114-U500 | 500 µg (5 x 100 µg) | $635.00 | ||
| 21-7114-M001 | 1 mg (10 x 100 µg) | $1,035.00 |
Technical Data Sheet
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Nesfatin-1 is a highly conserved metabolic polypetide derived through cleavage of its precursor protein, nucleobindin 2 (NUCB2). Nesfatin-1 is a secreted protein expressed in the hypothalamus and is implicated in regulation of appetite control and feeding behavior. It is described as an anorexigenic peptide and a satiety molecule. There is some indication that it plays a role in the adaptive response under stress conditions.
Nesfatin-1 is a highly conserved metabolic polypetide derived through cleavage of its precursor protein, nucleobindin 2 (NUCB2). Nesfatin-1 is a secreted protein expressed in the hypothalamus and is implicated in regulation of appetite control and feeding behavior. It is described as an anorexigenic peptide and a satiety molecule. There is some indication that it plays a role in the adaptive response under stress conditions.
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Product Details
| Name | Recombinant Human Nesfatin-1 (Carrier-free) |
|---|---|
| Cat. No. | 21-7114 |
| Alternative Names | NEFA Encoded Satiety and Fat-influencing protein 1, NUCB2 |
| Amino Acid Sequence | VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Measured through an in vivo assay where Nesfatin-1 is injected at 4 ?g/g of body weight into healthy wild type male C57BL/6J mice. Compared to saline-treated controls, significant effects on body weight and food consumption are expected. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human Nesfatin-1 consists of 82 amino acids and has a molecular weight of 9.7 kDa. |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Diabetes, Neurobiology |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.