Recombinant Human/Mouse/Rat Activin-A (Insect Cells) (Carrier-Free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-9071-U002 | 2 µg | $80.00 | ||
| 21-9071-U010 | 10 µg | $195.00 | ||
| 21-9071-U050 | 50 µg | $650.00 | ||
| 21-9071-U100 | 100 µg | $1,200.00 |
Lead time: 2-3 business days
Technical Data Sheet
Request Custom/BulkDescription
Activin A is a TGF-beta family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively.
Activin A is a TGF-beta family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively.
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Product Details
| Name | Recombinant Human/Mouse/Rat Activin-A (Insect Cells) (Carrier-Free) |
|---|---|
| Cat. No. | 21-9071 |
| Alternative Names | Inhibin beta-1, FRP, FSH (Follicle-stimulating hormone)-releasing protein |
| Amino Acid Sequence | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ? 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Human/Mouse/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 95 |
| Source | Hi-5 Insect cells. |
| Reactivity | Human, Mouse, Rat |
| Research Areas | Neurobiology, Stem Cells & Differentiation, TGF-Beta Superfamily, Angiogenesis/Cardiovascular, Apoptosis, Cancer |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.