Recombinant Human/Mouse/Rat Activin A (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8993-U002 | 2 µg | $76.00 | ||
| 21-8993-U010 | 10 µg | $175.00 | ||
| 21-8993-U100 | 100 µg | $895.00 | ||
| 21-8993-U500 | 500 µg | $2,945.00 |
Technical Data Sheet
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Activin A is a TGF-beta family member that exert a wide array of biological activities including regulation of cell proliferation and differentiation, apoptosis and metabolism. Activin A is one of four beta-subunit proteins that exist as homodimers or heterodimers of the beta-subunit isoforms. Activin protein complexes are closely related to inhibins, which consist of a beta-subunit paired with an alpha-subunit. Activins and inhibins are expressed by various cell types and mediate opposing biological effects. Human/Murine/Rat Activin A is a disulfide-linked homodimer consisting of two betaA chains.
Activin A is a TGF-beta family member that exert a wide array of biological activities including regulation of cell proliferation and differentiation, apoptosis and metabolism. Activin A is one of four beta-subunit proteins that exist as homodimers or heterodimers of the beta-subunit isoforms. Activin protein complexes are closely related to inhibins, which consist of a beta-subunit paired with an alpha-subunit. Activins and inhibins are expressed by various cell types and mediate opposing biological effects. Human/Murine/Rat Activin A is a disulfide-linked homodimer consisting of two betaA chains.
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Product Details
| Name | Recombinant Human/Mouse/Rat Activin A (Carrier-free) |
|---|---|
| Cat. No. | 21-8993 |
| Alternative Names | |
| Amino Acid Sequence | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ? 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Human/Mouse/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two beta-A chains, each containing 116 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 97 |
| Source | E. coli |
| Reactivity | Human, Mouse |
| Research Areas | Angiogenesis/Cardiovascular; Apoptosis; Cancer; Neurobiology; Stem Cells & Differentiation; TGF-beta Superfamily |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.