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Recombinant Human Maspin (Carrier-Free)
  • Recombinant Human Maspin (Carrier-Free)

Recombinant Human Maspin (Carrier-Free)

Cat No. Size Price Quantity
21-9091-U005 5 µg $80.00
21-9091-U020 20 µg $195.00
21-9091-U100 100 µg $600.00
21-9091-U500 500 µg $1,800.00

Description

Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells, but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the contribution of maspin to the inhibition of angiogenesis, and its ability to preferentially promote apoptosis of tumor cells.
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Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells, but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the contribution of maspin to the inhibition of angiogenesis, and its ability to preferentially promote apoptosis of tumor cells.
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Product Details

Name Recombinant Human Maspin (Carrier-Free)
Cat. No. 21-9091
Alternative Names SerpinB5, Protease inhibitor 5
Amino Acid Sequence MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LL
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Data not available at this time.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Maspin is a 42.1 kDa non-glycosylated protein containing 375 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 97
Source E.coli
Reactivity Human
Research Areas Wound Healing, Angiogenesis/Cardiovascular, Apoptosis, Cancer
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.