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Recombinant Human M-CSF (Carrier-free)
  • Recombinant Human M-CSF (Carrier-free)

Recombinant Human M-CSF (Carrier-free)

Cat No. Size Price Quantity
21-8789-U002 2 µg $45.00
21-8789-U010 10 µg $95.00
21-8789-U100 100 µg $675.00

Description

M-CSF, macrophage colony stimulating factor, is a hematopoietic growth factor important for driving differentiation, proliferation and maintenance of monocytes, macrophages, and other BM progenitor cells. M-CSF is produced by activated T cells and osteoclasts among other cell types. High levels of M-CSF in the pregnant uterus are associated with placenta formation and development. M-CSF activities include a variety of monocyte activities including enhanced phagocytic and chemotactic activity, and increased tumor cell cytotoxicity.
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M-CSF, macrophage colony stimulating factor, is a hematopoietic growth factor important for driving differentiation, proliferation and maintenance of monocytes, macrophages, and other BM progenitor cells. M-CSF is produced by activated T cells and osteoclasts among other cell types. High levels of M-CSF in the pregnant uterus are associated with placenta formation and development. M-CSF activities include a variety of monocyte activities including enhanced phagocytic and chemotactic activity, and increased tumor cell cytotoxicity.
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Product Details

Name Recombinant Human M-CSF (Carrier-free)
Cat. No. 21-8789
Alternative Names Macrophage Colony Stimulating Factor, CSF-1, MGI-IM
Amino Acid Sequence MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity ED50 determined by the dose-dependent stimulation of the proliferation of Mouse M-NSF-60 cells ? 1 ng/ml, corresponding to a specific activity of ≥1 x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human M-CSF is a 36.8 kDa homodimeric protein composed of two 159 amino acid polypeptide subunits.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Cancer; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.