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Recombinant Human KGF (FGF-7) (Carrier-free)
  • Recombinant Human KGF (FGF-7) (Carrier-free)

Recombinant Human KGF (FGF-7) (Carrier-free)

Cat No. Size Price Quantity
21-8700-U002 2 µg $69.00
21-8700-U010 10 µg $199.00
21-8700-U100 100 µg $1,025.00
21-8700-U500 500 µg $3,100.00

Description

Keratinocyte Growth Factor (KGF/FGF-7) is a member of the FGF family and is secreted by cells of mesenchymal origin. KGF plays a role in kidney and lung development, angiogenesis, wound healing, and migration and differentiation of epithelial cells. Expression of KGF is upregulated in skin after injury. This growth factor signals through binding of a splice variant of the FGFR2 that is predominantly expressed on epithelial cells.
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Keratinocyte Growth Factor (KGF/FGF-7) is a member of the FGF family and is secreted by cells of mesenchymal origin. KGF plays a role in kidney and lung development, angiogenesis, wound healing, and migration and differentiation of epithelial cells. Expression of KGF is upregulated in skin after injury. This growth factor signals through binding of a splice variant of the FGFR2 that is predominantly expressed on epithelial cells.
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Product Details

Name Recombinant Human KGF (FGF-7) (Carrier-free)
Cat. No. 21-8700
Alternative Names Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Amino Acid Sequence CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ? 10 ng/ml, corresponding to a specific activity of ≥≥≤ 1 x 105 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; FGF Superfamily; Proliferation; Stem Cells & Differentiation; Wound Healing
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.