Recombinant Human IL-7 (E. coli Derived) (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8079-U002 | 2 µg | $69.00 | ||
| 21-8079-U010 | 10 µg | $175.00 | ||
| 21-8079-U100 | 100 µg | $885.00 |
Technical Data Sheet
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IL-7 is a hemopoietin family member that factor is produced by bone marrow, thymic stromal cells and spleen cells, among others. This cytokine is a growth factor for progenitor B cells and T cells that signals through the IL-7R, comprised of IL-7Ralpha (CD127) and the common gamma chain (CD132). IL7 is required for optimal T celldendritic cell interaction and contributes to T-cell homeostasis.
IL-7 is a hemopoietin family member that factor is produced by bone marrow, thymic stromal cells and spleen cells, among others. This cytokine is a growth factor for progenitor B cells and T cells that signals through the IL-7R, comprised of IL-7Ralpha (CD127) and the common gamma chain (CD132). IL7 is required for optimal T celldendritic cell interaction and contributes to T-cell homeostasis.
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Product Details
| Name | Recombinant Human IL-7 (E. coli Derived) (Carrier-free) |
|---|---|
| Cat. No. | 21-8079 |
| Alternative Names | Lymphopoietin 1(LP-1), pre-B cell factor |
| Amino Acid Sequence | MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Cancer; Inflammation; Stem Cells & Differentiation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.