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Recombinant Human IL-7 (E. coli Derived) (Carrier-free)
  • Recombinant Human IL-7 (E. coli Derived) (Carrier-free)

Recombinant Human IL-7 (E. coli Derived) (Carrier-free)

Cat No. Size Price Quantity
21-8079-U002 2 µg $69.00
21-8079-U010 10 µg $175.00
21-8079-U100 100 µg $885.00

Description

IL-7 is a hemopoietin family member that factor is produced by bone marrow, thymic stromal cells and spleen cells, among others. This cytokine is a growth factor for progenitor B cells and T cells that signals through the IL-7R, comprised of IL-7Ralpha (CD127) and the common gamma chain (CD132). IL­7 is required for optimal T cell­dendritic cell interaction and contributes to T-cell homeostasis.
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IL-7 is a hemopoietin family member that factor is produced by bone marrow, thymic stromal cells and spleen cells, among others. This cytokine is a growth factor for progenitor B cells and T cells that signals through the IL-7R, comprised of IL-7Ralpha (CD127) and the common gamma chain (CD132). IL­7 is required for optimal T cell­dendritic cell interaction and contributes to T-cell homeostasis.
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Product Details

Name Recombinant Human IL-7 (E. coli Derived) (Carrier-free)
Cat. No. 21-8079
Alternative Names Lymphopoietin 1(LP-1), pre-B cell factor
Amino Acid Sequence MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Cancer; Inflammation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.