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Recombinant Human IL-36α (IL-1F6) (Carrier-free)
  • Recombinant Human IL-36α (IL-1F6) (Carrier-free)

Recombinant Human IL-36α (IL-1F6) (Carrier-free)

Cat No. Size Price Quantity
21-9226-U002 2 µg $70.00
21-9226-U010 10 µg $180.00
21-9226-U100 100 µg $995.00
21-9226-U250 250 µg $1,750.00
21-9226-U500 500 µg $3,050.00
21-9226-M001 1 mg (2 x 500 µg) $4,900.00

Description

Human interleukin‑36 alpha, previously known as IL-1F6, is a member of the IL-1 family of proteins. Cells reported to express IL‑36 alpha include monocytes, B cells, and T cells. IL‑36 alpha is the only IL‑1 family member found to be expressed on T cells and is implicated in skin homeostasis. It is reported to be highly expressed in psoriatic plaques. Recombinant Human IL-36α is a 17.2 kDa protein containing 154 amino acid residues.
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Human interleukin‑36 alpha, previously known as IL-1F6, is a member of the IL-1 family of proteins. Cells reported to express IL‑36 alpha include monocytes, B cells, and T cells. IL‑36 alpha is the only IL‑1 family member found to be expressed on T cells and is implicated in skin homeostasis. It is reported to be highly expressed in psoriatic plaques. Recombinant Human IL-36α is a 17.2 kDa protein containing 154 amino acid residues.
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Product Details

Name Recombinant Human IL-36α (IL-1F6) (Carrier-free)
Cat. No. 21-9226
Alternative Names Interleukin-36α, IL36A, Interleukin-1 family member 6 (IL-1F6), FIL1ε (FIL1E), Interleukin-1ε (IL1E)
Amino Acid Sequence MKIDTPQQGS IQDINHRVWV LQDQTLIAVP RKDRMSPVTI ALISCRHVET LEKDRGNPIY LGLNGLNLCL MCAKVGDQPT LQLKEKDIMD LYNQPEPVKS FLFYHSQSGR NSTFESVAFP GWFIAVSSEG GCPLILTQEL GKANTTDFGL TMLF
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Measured by its ability to induce IL-8 secretion by A431 human epidermoid carcinoma cells.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass 17.2 kDa
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Cancer, Diabetes/Weight Regulation, Immune System, Inflammation, Neurobiology
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.