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Recombinant Human IL-3 (Carrier-free)
  • Recombinant Human IL-3 (Carrier-free)

Recombinant Human IL-3 (Carrier-free)

Cat No. Size Price Quantity
21-8039-U002 2 µg $61.00
21-8039-U010 10 µg $150.00
21-8039-U100 100 µg $510.00

Description

IL-3 is a major hematopoietic growth factor produced by basophils and activated T cells and drives the differentiation of hematopoietic stem cells into myeloid lineages precursors. In conjunction with IL-7, IL-3 will induce lymphoid precursor cell differentiation. Together with other cytokines including EPO, GM-CSF, and IL-6 in an immune response, IL-3 will support growth and differentiation of T cells from the bone marrow.
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IL-3 is a major hematopoietic growth factor produced by basophils and activated T cells and drives the differentiation of hematopoietic stem cells into myeloid lineages precursors. In conjunction with IL-7, IL-3 will induce lymphoid precursor cell differentiation. Together with other cytokines including EPO, GM-CSF, and IL-6 in an immune response, IL-3 will support growth and differentiation of T cells from the bone marrow.
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Product Details

Name Recombinant Human IL-3 (Carrier-free)
Cat. No. 21-8039
Alternative Names MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
Amino Acid Sequence APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human IL-3 is a 15.0 kDa protein of 133 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV; Cancer; Cell Culture; Immune System; Proliferation; Stem Cells & Differentiation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.