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Recombinant Human IL-23 (Carrier-free)
  • Recombinant Human IL-23 (Carrier-free)

Recombinant Human IL-23 (Carrier-free)

Cat No. Size Price Quantity
21-8323-U002 2 µg $88.00
21-8323-U010 10 µg $249.00
21-8323-U100 100 µg $1,750.00
21-8323-U500 500 µg $5,985.00

Description

IL-23 is a disulfide-linked heterodimeric protein consisting of a p19 subunit unique to IL-23 and a p40 subunit that is shared with IL-12. IL-23 is proinflamatory and expressed by activated dendritic cells and macrophages. IL-23 drives the differentiation of Th17 cells in vivo and induces the proliferation of memory T cells.
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IL-23 is a disulfide-linked heterodimeric protein consisting of a p19 subunit unique to IL-23 and a p40 subunit that is shared with IL-12. IL-23 is proinflamatory and expressed by activated dendritic cells and macrophages. IL-23 drives the differentiation of Th17 cells in vivo and induces the proliferation of memory T cells.
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Product Details

Name Recombinant Human IL-23 (Carrier-free)
Cat. No. 21-8323
Alternative Names Toll-Like Receptor 4, ARMD10
Amino Acid Sequence p19 subunit: RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP p40 subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWT
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Measured by its ability to induce IL-17 secretion by mouse splenocytes.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids).
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 95
Source (BTI-Tn-5B1-4) Hi-5 Insect cells
Reactivity Human
Research Areas Cancer; Immune System; Inflammation; Allergy
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.