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Recombinant Human IL-1ß (Carrier-free)
  • Recombinant Human IL-1ß (Carrier-free)

Recombinant Human IL-1ß (Carrier-free)

Cat No. Size Price Quantity
21-8018-U002 2 µg $61.00
21-8018-U010 10 µg $175.00
21-8018-U100 100 µg $895.00
21-8018-U500 500 µg $2,095.00

Description

IL-1 beta is a proinflammatory cytokine produced by activated macrophages that functions as a T and B cell mitogen. IL-1 beta is structurally related to IL-1 alpha and although both proteins are regulated independently, they exert similar biological effect in response to inflammatory agents.
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IL-1 beta is a proinflammatory cytokine produced by activated macrophages that functions as a T and B cell mitogen. IL-1 beta is structurally related to IL-1 alpha and although both proteins are regulated independently, they exert similar biological effect in response to inflammatory agents.
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Product Details

Name Recombinant Human IL-1α (Carrier-free)
Cat. No. 21-8018
Alternative Names Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Amino Acid Sequence APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine D10S cells is ? 1.0 pg/ml, corresponding to a specific activity of ≥ 1x 109 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human IL-1? is a 17.3 kDa protein consisting of 153 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Angiogenesis/Cardiovascular; Cancer; Diabetes / Weight Regulation; Immune System; Inflammation; Neurobiology; Proliferation; Stem Cells & Differentiation; Wound Healing; Allergy; Transplantation
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.