Recombinant Human IL-17E (IL-25) (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8736-U005 | 5 µg | $76.00 | ||
| 21-8736-U025 | 25 µg | $175.00 | ||
| 21-8736-U100 | 100 µg | $525.00 | ||
| 21-8736-U500 | 500 µg | $1,795.00 |
Technical Data Sheet
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IL-17E, also known as IL-25, belongs to the IL-17 family of immunoregulatory cytokines which are secreted as homodimers. Unlike other IL-17 family members, IL-17E promotes Th2 biased immune responses. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17E is an important mediator of allergic reactions and provides protection against intestinal parasites.
IL-17E, also known as IL-25, belongs to the IL-17 family of immunoregulatory cytokines which are secreted as homodimers. Unlike other IL-17 family members, IL-17E promotes Th2 biased immune responses. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17E is an important mediator of allergic reactions and provides protection against intestinal parasites.
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Product Details
| Name | Recombinant Human IL-17E (IL-25) (Carrier-free) |
|---|---|
| Cat. No. | 21-8736 |
| Alternative Names | IL-25 |
| Amino Acid Sequence | MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100 ng. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | Inflammation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.