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Recombinant Human IL-16 (130 a.a.) (Carrier-Free)
  • Recombinant Human IL-16 (130 a.a.) (Carrier-Free)

Recombinant Human IL-16 (130 a.a.) (Carrier-Free)

Cat No. Size Price Quantity
21-9125-U002 2 µg $80.00
21-9125-U010 10 µg $195.00
21-9125-U050 50 µg $624.00
21-9125-U100 100 µg $1,040.00

Description

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. Human and Mouse IL-16 show significant cross-species reactivity.
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IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. Human and Mouse IL-16 show significant cross-species reactivity.
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Product Details

Name Recombinant Human IL-16 (130 a.a.) (Carrier-Free)
Cat. No. 21-9125
Alternative Names LCF (Lymphocyte Chemoattractant Factor)
Amino Acid Sequence PDLNSSTDSA ASASAASDVS VESTAEATVC TVTLEKMSAG LGFSLEGGKG SLHGDKPLTI NRIFKGAASE QSETVQPGDE ILQLGGTAMQ GLTRFEAWNI IKALPDGPVT IVIRRKSLQS KETTAAGDS
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity Determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 1.0-100.0 ng/ml.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV, Inflammation, Immune System, Apoptosis
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.