Recombinant Human IL-15 (Carrier-free)
| Cat No. | Size | Price | Quantity | |
|---|---|---|---|---|
| 21-8157-U002 | 2 µg | $69.00 | ||
| 21-8157-U010 | 10 µg | $195.00 | ||
| 21-8157-U100 | 100 µg | $750.00 | ||
| 21-8157-U500 | 500 µg | $2,095.00 |
Technical Data Sheet
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IL-15 is constitutively expressed by multiple cell types including monocytes, macrophages, dendritic cells, keratinocytes, fibroblasts, nerve cells. It is a member of the IL-2 family and shares similarities to IL-2. IL-15 has a key role in a number of areas spanning innate and adaptive immunity. IL-15 has a primary target of T cells but also acts on NK cells causing both cell types to proliferate. Elevated quantities of IL-15 are associated with its role in autoimmune diseases and retroviral disease, at least HIV-1 and HTLV-1.
IL-15 is constitutively expressed by multiple cell types including monocytes, macrophages, dendritic cells, keratinocytes, fibroblasts, nerve cells. It is a member of the IL-2 family and shares similarities to IL-2. IL-15 has a key role in a number of areas spanning innate and adaptive immunity. IL-15 has a primary target of T cells but also acts on NK cells causing both cell types to proliferate. Elevated quantities of IL-15 are associated with its role in autoimmune diseases and retroviral disease, at least HIV-1 and HTLV-1.
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Product Details
| Name | Recombinant Human IL-15 (Carrier-free) |
|---|---|
| Cat. No. | 21-8157 |
| Alternative Names | IL-T |
| Amino Acid Sequence | MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Bioactivity | ED50 calculated at ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg by proliferation assays of CTLL-2 cells. |
| Endotoxin Level | Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg). |
| Molecular Mass | Recombinant Human IL-15 is a 12.9 kDa protein consisting of 114 amino acid residues. |
| Protein Content | Content Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Purity (%) | 98 |
| Source | E. coli |
| Reactivity | Human |
| Research Areas | AIDS/HIV; Apoptosis; Cancer; Cell Culture; Immune System; Inflammation; Stem Cells & Differentiation |
| Reconstitution | See Certificate of Analysis (COA) for lot specific reconstitution information. |
| Application | Bioassay |
Application Key:
FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.