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Recombinant Human IL-13 (Carrier-free)
  • Recombinant Human IL-13 (Carrier-free)

Recombinant Human IL-13 (Carrier-free)

Cat No. Size Price Quantity
21-8139-U002 2 µg $69.00
21-8139-U010 10 µg $195.00
21-8139-U100 100 µg $1,140.00
21-8139-U500 500 µg $2,560.00

Description

IL-13, produced primarily by Th2 cells and to a lesser extent by mast and NK cells, is an immunoregulatory cytokine. Its various functions include induction of matrix metalloproteinases, enhancement of IgE secretion from activated B cells and B cell proliferation. Additionally, IL-13 plays a role in the inhibition of the expression of inflammatory cytokines including IL-1?, TNF-αα, IL-6 and IL-8.
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IL-13, produced primarily by Th2 cells and to a lesser extent by mast and NK cells, is an immunoregulatory cytokine. Its various functions include induction of matrix metalloproteinases, enhancement of IgE secretion from activated B cells and B cell proliferation. Additionally, IL-13 plays a role in the inhibition of the expression of inflammatory cytokines including IL-1?, TNF-αα, IL-6 and IL-8.
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Product Details

Name Recombinant Human IL-13 (Carrier-free)
Cat. No. 21-8139
Alternative Names NC30
Amino Acid Sequence MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ? 1.0 ng/ml, corresponding to a specific activity of ≥ 1x 106 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human IL-13 is a 12.6 kDa protein composed of 115 amino acid residues.
Protein Content Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas AIDS/HIV; Cancer; Immune System; Inflammation; Stem Cells & Differentiation; Allergy
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.