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Recombinant Human Growth Hormone (Carrier-free)
  • Recombinant Human Growth Hormone (Carrier-free)

Recombinant Human Growth Hormone (Carrier-free)

Cat No. Size Price Quantity
21-7147-U010 10 µg $69.00
21-7147-U050 50 µg $169.00
21-7147-U100 100 µg $205.00
21-7147-U500 500 µg $455.00

Description

Growth Hormone (GH), also known as somatotropin, is a secreted protein that is best known for stimulating the growth and differentiation of bone, cartilage and muscle. It stimulates the production of IGF-1, involved in the regulation of growth and metabolism. GH also can act on B cells, T cells, NK cells, macrophages and neutrophils to exert immunomodulatory actions directly or indirectly through IGF-1. Its varied functions are associated with binding to its receptor, which is present on a wide array of cell types. GH is synthesized by somatotropes in the anterior pituitary and is stored in secretory granules. Release into circulation is tightly regulated by hypothalamic hormones and other signals.
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Growth Hormone (GH), also known as somatotropin, is a secreted protein that is best known for stimulating the growth and differentiation of bone, cartilage and muscle. It stimulates the production of IGF-1, involved in the regulation of growth and metabolism. GH also can act on B cells, T cells, NK cells, macrophages and neutrophils to exert immunomodulatory actions directly or indirectly through IGF-1. Its varied functions are associated with binding to its receptor, which is present on a wide array of cell types. GH is synthesized by somatotropes in the anterior pituitary and is stored in secretory granules. Release into circulation is tightly regulated by hypothalamic hormones and other signals.
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Product Details

Name Recombinant Human Growth Hormone (Carrier-free)
Cat. No. 21-7147
Alternative Names GH1, GH, Somatotrophin, GH-N, Pituitary Growth Hormone, HGH
Amino Acid Sequence MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Bioactivity The expected ED50 of ≤ 0.05 ng/ml is determined by its ability to stimulate the proliferation of Nb2-11 cells in rat, and corresponds to a specific activity of ≥ 2 x 107 units/mg.
Endotoxin Level Endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Molecular Mass Recombinant Human Growth Hormone is a non-glycosylated polypeptide consisting of 192 amino acids and has a molecular weight of ≥ 22.3 kDa.
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Purity (%) 98
Source E. coli
Reactivity Human
Research Areas Proliferation, Immune System, Bone and Cartilage, Chemotaxis, Wound Healing, AIDS/HIV, Cell Culture
Reconstitution See Certificate of Analysis (COA) for lot specific reconstitution information.
Application Bioassay
Application Key:

FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy

*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.